John Y. Lee
Mr. Lee is a former FDA Investigator. His area of expertise includes pharmaceutical and API GMPs, pre-approval inspections and sterile products. He specializes in the development of practical GMP training courses and workshops.
Professional Experience
8/91 – Present
Executive Director, Pharmaceutical Compliance Associates
Massapequa, New York
Henderson, Nevada
3/88 – 8/91
Director, Quality Assurance and Quality Control, Altana, Inc.
Melville, New York
4/85 – 3/88
Quality Assurance Manager, Organon, Inc.
West Orange, New Jersey
12/83 – 4 /85
GMP Compliance Associate, Ortho Pharmaceutical Corporation (Div. Johnson & Johnson)
Raritan, New Jersey
10/77 – 12/83
Consumer Safety Officer (Investigator), U.S. Food & Drug Administration (FDA)
East Orange, New Jersey
Technical Experience
- Extensive GMP auditing and consultation experience in active pharmaceutical ingredients (API) and finished pharmaceuticals, with specialization in pre-approval inspection (PAI) audits and sterile products.
- Active involvement in the design, renovation and validation of sterile and non-sterile pharmaceutical facilities.
- Designed validation studies, prepared validation documents, and coordinated validation projects for sterile and non-sterile operations.
- Developed and organized Quality Assurance operations and programs including batch record review, product annual reviews, documentation control, quality assurance investigation, auditing, GMP and technical training, validation, product stability, and deviation/OOS investigations.
- Developed and presented training programs for line personnel, supervisors and management on topics of GMP compliance, validation, quality assurance programs, and sterilization science.
Publications
- “Checklist for Computer Software Validation,” Pharmaceutical Technology, February 2014.
- “Change Management: Common Failures and a Checklist for Improvement,” Pharmaceutical Technology Europe, May 2010.
- “Product Annual/Quality Review: US/EU Comparative Analysis and Interpretations,” Phamaceutical Technology, 32(3): 88-104, March, 2008
- “Good Laboratory Practices (GLP) Regulations: Interpretation Techniques and Review of Selected Compliance Issues,” Drug Information Journal, 40(1): 33-38, 2006
- “FDA Compliance Issues For Cleaning Validation,” STP Pharma Pratiques, 10(5): 292-295, September-October, 2000.
- “Documentation Requirements for Preapproval Inspections,” Pharmaceutical Technology, 17(3):154-164, March, 1993.
- “Validation Organization and Documentation,” Pharm Tech Japan, 9(2):151-161, February, 1993.
- “Recent Trends in Process Validation,” chapter in Pharmaceutical Process Validation, Marcel Dekker, Inc., New York, 573-586, 1993.
- “Validation Terminology and Concepts,” Pharm Tech Japan, 8(9):7-16, September, 1992.
- “Sterilization Control and Validation for Topical Ointments,” Pharmaceutical Technology, 16(3):104-110, March, 1992.
- “Product Annual Review,” Pharmaceutical Technology, 14(4):86-92, April, 1990.
- “Investigating Sterility Test Failures,” Pharmaceutical Technology, 14(2):38-43, February, 1990.
- “Validating an Automated Filter Integrity Test Instrument,” Pharmaceutical Technology, 13(10):48-56, October, 1989.
- “Security for Pharmaceutical Audit Reports,” Pharmaceutical Production TechSource, 4(6):3, June 1989.
- “Auditing an Aseptic Filtration Process,” Pharmaceutical Technology, 13(2):66-72, February, 1989.
- “Environmental Requirements for Clean Rooms,” Bio-Pharm, 1(7):40-43, 1988 reprinted 2(2):42-45, February, 1989.
- “GMP Compliance for the Lyophilization of Parenterals: Part II,” Pharmaceutical Technology, 12(11):38-42, November, 1988.
- “GMP Compliance for the Lyophilization of Parenterals: Part I,” Pharmaceutical Technology, 12(10):54-60, October, 1988.
- “Essential Elements for Establishing and Performing an Internal GMP Audit,” Pharmaceutical Manufacturing, 3(2):18-21, February, 1986.
- “GMP Compliance for Clinical Packaging,” Pharmaceutical Manufacturing, 2(9):34-38, September, 1985.
Courses & Lectures
Course director, symposium chairman, moderator and trainer/speaker for professional organizations:
- PharmaNet, Inc.
- Parenteral Drug Association
- The Center for Professional Advancement
- Pharm-Tech Conference
- Medical Manufacturing TechSource
- American Society for Microbiology
- Institute for Applied Pharmaceutical Science
- InfoScience
- Technical Seminars
Education
MBA – Pharmaceutical Studies, Fairleigh Dickinson University, Teaneck, New Jersey, 1991
BA – Biology, New York University, New York, New York, 1976
Professional Affiliations
- Founder of the GMP Compliance Network
- Former Vice President of the North Jersey Chapter of the International Society for Pharmaceutical Engineering (ISPE)
- Former Vice President of the GMP Education and Training Association
- Member of the Parenteral Drug Association